Molecular machines are nanoscale macromolecular complexes performing specific functions for an organism. Cells build thousands of such custom-designed complexes including the ribosome, transcriptional machinery, motors and transporters, all of which work in a precisely organized manner. Knowledge of their properties is of crucial importance in bionanotechnology.

Joanna Trylska and her group explore the function, dynamics, and physical properties of macromolecular assemblies to understand their activities in the cell. The main object of our studies is the ribosome - the ribonucleoprotein complex responsible for protein synthesis. The ultimate goal is to search for antibiotic analogs inhibiting the function of bacterial ribosomes.

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Centre of New Technologies University of Warsaw Żwirki i Wigury 93 02-089 Warsaw, Poland tel. +48 (22) 5540-800 fax +48 (22) 5540-801 joanna@cent.uw.edu.pl

 

Funding

  • National Centre for Research and Development
  • National Science Centre
  • Polish Ministry of Science and Higher Education
  • Foundation for Polish Science
  • European Union, European Regional Development Fund

 

 

Biomolecular Machines Laboratory logo by Krzysztof Rychter