Name: Tomasz Pieńko

Nationality: Polish

Current Position:

PhD Student



Centre of New Technologies

University of Warsaw


 

Contact:

email: tom.pienko@gmail.com

phone: +48 22 55 43 682


fax: +48 22 55 40 801

Office Address:

Centre of New Technologies

Banacha 2C, 02-097 Warsaw, Poland

Room number: 402


 

Education:

  • 2015-present: PhD studies at the Centre of New Technologies, University of Warsaw & Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw 
  • 2009-2015: studies at the Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Master of Pharmacy 

Conferences and Workshops:

  • A. P. Mazurek, P. P. Taciak, T. Pieńko, ,,Synthesis and determination of conformations of new serotonin receptor ligands'', 31st Camerino-Cyprus-Noordwijkerhout Symposium, Camerino, May 19-23, 2013.
  • K. Młodzikowska, T. Pieńko, P. P. Taciak, "Computational study of the 8-phenylsulphanyI-4-trifluoromethyl-2-piperazin-l-yl-quinoline of potential dual action: agonistic of 5-HT IB receptor and SERT inhibition", The 14th International Congress of Young Medical Scientists, May 9-10, 2014, Poznań, Poland.
  • P. P. Taciak, R Wyrębiak, T. Pieńko, A. P. Mazurek "Synthesis and determination of conformations of new serotonin receptor ligands", VI Konwersatorium Chemii Medycznej Lublin, 18-20 września 2014.
  • K. Młodzikowska, T. Pieńko, P. P. Taciak. Computational study of quinoline derivatives witb potential 5-HT IB receptor agonistic. VI Konwersatorium Chemii Medycznej Lublin 18-20 września 2014.
  • K Młodzikowska, T. Pieńko, P. P. Taciak, ,,Pochodne chinoliny o potencjalnej aktywności wobec receptora 5-HTIB i inhibicji SERT- analiza w ujęciu chemii obliczeniowej", V Ogólnopolska Konferencja dla lekarzy, naukowców i studentów. Postępy w Badaniach Biomedycznych", 29 listopada 2014, Warszawa.
  • KDM session 2016, June 20. Okeanos supercomputer benchmark as a part of GES-10.
  • T. Pieńko, A. Wierzba, M. Wojciechowska, D. Gryko, J. Trylska. Conformational dynamics of vitamin B12-peptide nucleic acid conjugates revealed with molecular dynamics approach. Modeling and Design of Molecular Materials, 2016, June 26-30, Trzebnica, Poland, poster presentation.
  • T. Pieńko, J. Trylska. Transport of Vitamin B12 and its Conjugate with Peptide Nucleic Acid Through the E. Coli BtuB Outer Membrane Protein Explored with Steered Molecular Dynamics. Biophysical Society 61st Annual Meeting, February 11-15, 2017, New Orleans, USA, poster presentation.
  • T. Pieńko, J. Trylska. Transport of Vitamin B12 and its Conjugate with Peptide Nucleic Acid Through the E. Coli BtuB Outer Membrane Protein Explored with Steered Molecular Dynamics. XIX ICM Users Session, April 19-21, 2017, Warsaw, Poland, oral presentation.
  • T. Pieńko, J. Trylska, The role of BtuB dynamics in the transport of vitamin B12 through E.coli outer membrane. 5th European Joint Theoretical / Experimental Meeting On Membranes, December 6-8, 2017, Cracow, Poland, poster presentation. 

Publications:

  • T. Pieńko „Kapsaicyna- właściwości, zastosowania i perspektywy”, Biul. Wydz. Farm. WUM, 2013, 2, 11-17.
  • T. Pieńko, P.P. Taciak, A.P. Mazurek. On the basicity of 8-phenylsulfanyl quipazine derivatives: new potential serotonergic agents. J. Phys. Chem. A, 2015, 119(27), 6989-6999.
  • T. Pieńko, M. Grudzień, P.P. Taciak, A.P. Mazurek. Cytisine basicity, solvation, logP, and logD theoretical determination as tool for bioavailability prediction. J. Mol. Graph. Model., 2016, 63, 15-21.
  • T. Pieńko, A.J. Wierzba, M. Wojciechowska, D. Gryko, J. Trylska. Conformational dynamics of cyanocobalamin and its conjugates with peptide nucleic acids. J. Phys. Chem. B, 2017, 121(14), 2968-2979.
  • T. Pieńko, M. Grudzień, P.P. Taciak, A.P. Mazurek. Adsorption of antifungal drugs inside pristine and functionalized fullerenes and nanotubes: DFT investigation. Curr. Comput. Aided Drug Des. 2017, 13(3), 177-185.
  • M. Równicki, T. Pieńko, J. Czarnecki, M. Kolanowska, D. Bartosik, J. Trylska, Artificial activation of Escherichia coli mazEF and hipBA toxin–antitoxin systems by antisense peptide nucleic acids as an antibacterial strategy, Front. Microbiol. 9:2870, 2018
  • B. Smolkin, A. Khononov, T. Pieńko, M. Shavit, V. Belakhov, J. Trylska, T. Baasov, Towards catalytic antibiotics: redesign of aminoglycosides to catalytically disable bacterial ribosomes, ChemBioChem, 2018
  • N. Sabbavarapu, T. Pieńko, B. H. Zalman, J. Trylska, T. Baasov, Exploring eukaryotic versus prokaryotic ribosomal RNA recognition with aminoglycoside derivatives, Med. Chem. Commun., 9:503-508, 2018
  • A. Dąbrowska, T. Pieńko, P. Taciak, K. Wiktorska, Z. ChilmonczykA. P. MazurekA. StasiulewiczFullerene Derivatives of Nucleoside HIV Reverse Transcriptase Inhibitors-In Silico Activity Prediction. Int J Mol Sci. 2018 Oct; 19(10): 3231.