Project title: Antisense peptide nucleic acids as inhibitors of bacterial translation

The main objective of the Team project is to apply both computational and experimental techniques to design specific peptide nucleic acid (PNA) derivatives that will target the ribosomal RNA and inhibit bacterial translation.

Project period: Nov 2009 – Oct 2013

Research partners:

  • University of California at San Diego, CA,
  • University of Virginia, Charlottesville, VA,
  • NEST, Scuola Normale Superiore, Pisa, Italy